Famotidine, a histamine H2 receptor, plays a key role in reducing stomach acid production. By binding to the stomach's acid-producing receptors, famotidine inhibits their ability to create acid for a certain period.



Is Famotidine Safe for Cats?

Famotidine is widely regarded as a safe medication for cats, dogs, and horses. However, it's crucial to consult your veterinarian before administering it to your feline companion. The Federal Drug Administration (FDA) states that using famotidine for treating ulcers in cats, dogs, and small mammals is considered "off-label." While not officially approved, veterinarians have the discretion to utilize it for this purpose under extra-label drug use (ELDA) guidelines.


Dr. Julie Parks, a Doctor of Veterinary Medicine at Northwood Hills Animal Hospital, explains that famotidine is commonly used to treat gastric ulcers in pets. In some cases, it is administered to prevent ulcers in pets that are highly sensitive to non-steroidal anti-inflammatory drugs. The occurrence of side effects associated with famotidine usage is rare. However, a study suggests that prolonged use may decrease its effectiveness in cats.


Understanding the Uses of Famotidine in Cats

Famotidine serves various purposes for cats, particularly those experiencing gastrointestinal issues involving the mouth, esophagus, stomach, and intestines. It can be administered orally, intravenously, or intramuscularly, but caution should be exercised when giving it intravenously to avoid vomiting and irregular heartbeat.


Stomach Ulcers

Stomach ulcers are caused by the erosion of the stomach's protective lining due to natural acid. This condition leads to a burning sensation, nausea, vomiting, and reduced appetite. For cats, inappetence is concerning as it can quickly result in fatty liver syndrome (hepatic lipidosis) if they don't eat for 48 hours. Famotidine helps alleviate the symptoms and encourages eating.


Stomach Inflammation Secondary to Kidney Disease

Senior cats, typically over 8 years old, are prone to kidney disease. Reduced kidney function can cause stomach inflammation, resulting in nausea, vomiting, and loss of appetite. Administering famotidine helps alleviate these symptoms, making it easier for cats to eat despite stomach discomfort.

As cats grow older, a considerable number of them undergo varying degrees of kidney disease.

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Esophageal Ulceration or Inflammation

Famotidine provides relief to cats with irritated, inflamed, or ulcerated esophagus. Inflamed esophagus can occur after surgical intubation, leading to discomfort. This medication can also help soothe the effects of repetitive vomiting, acid reflux, or medication-induced damage to the esophagus.


Side Effects

The most commonly reported side effect of famotidine usage in cats is diarrhea, though it is rare. In human trials, side effects such as vomiting, loss of appetite, headache, dry mouth, and dry skin were observed. Instances of low white blood cell count in cats on famotidine are extremely rare. If your cat experiences any side effects, it's best to contact your veterinarian immediately.


Precautions

Elderly pets should receive a reduced dose of famotidine, particularly when administered intravenously. Cats with pre-existing heart, liver, or kidney disease should be carefully monitored if given famotidine.


Famotidine Dosage Chart for Cats

Always follow your veterinarian's instructions and complete the prescribed course, even if your cat seems fully recovered. The typical famotidine dose for cats is 5 mg every 12 to 24 hours. For extended treatment, the minimum effective dose (MED) is recommended. If famotidine does not show desired results, consult your veterinarian for further guidance. Administer famotidine on an empty stomach, at least 30 minutes before meals or other medications. If nausea or vomiting occurs, administer famotidine with a small amount of food or a treat. Liquid forms of famotidine are available, and veterinarians can administer it intravenously or intramuscularly if necessary.


Conclusion

Famotidine proves to be a valuable medication for preventing and treating stomach and esophageal ulcers or inflammation in cats. Side effects are rare and generally mild. It is crucial to consult your veterinarian before administering any medication to your cat. Always prioritize your pet's health and well-being